Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lgi2Leucine-rich repeat LGI family, member 2b. (546 aa)    
Predicted Functional Partners:
adam23
ADAM metallopeptidase domain 23.
     
 0.866
ADAM11
ADAM metallopeptidase domain 11.
     
 0.684
adam22
ADAM metallopeptidase domain 22.
     
 0.684
LOC103481264
Uncharacterized protein.
     
 0.684
LOC103475426
Lipase, member Ia.
      
 0.518
zcchc4
Zinc finger, CCHC domain containing 4.
      
 0.515
Fbxl17
F-box domain-containing protein.
   
 
 0.478
ENSPREP00000023888
Uncharacterized protein.
   
 
 0.478
LOC103481180
Bromo domain-containing protein.
    
 0.468
LOC103481495
Zgc:174164.
     
 0.408
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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