node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103458631 | hmg20a | ENSPREP00000002417 | ENSPREP00000018594 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | High mobility group 20A. | 0.523 |
LOC103458631 | hmg20b | ENSPREP00000002417 | ENSPREP00000012358 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | High mobility group 20B. | 0.682 |
LOC103458631 | kdm1a | ENSPREP00000002417 | ENSPREP00000006670 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.853 |
LOC103458631 | phf21a | ENSPREP00000002417 | ENSPREP00000030809 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | PHD finger protein 21Ab. | 0.697 |
LOC103458631 | rcor1 | ENSPREP00000002417 | ENSPREP00000006226 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 1. | 0.767 |
LOC103458631 | rcor2 | ENSPREP00000002417 | ENSPREP00000001173 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 2. | 0.657 |
LOC103458631 | rcor3 | ENSPREP00000002417 | ENSPREP00000033517 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | REST corepressor 3. | 0.657 |
LOC103458631 | rest | ENSPREP00000002417 | ENSPREP00000016933 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | RE1-silencing transcription factor. | 0.578 |
LOC103458631 | znf217 | ENSPREP00000002417 | ENSPREP00000031244 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Zinc finger protein 217. | 0.417 |
glyr1 | kdm1a | ENSPREP00000017056 | ENSPREP00000006670 | Glyoxylate reductase 1 homolog (Arabidopsis). | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.885 |
hmg20a | LOC103458631 | ENSPREP00000018594 | ENSPREP00000002417 | High mobility group 20A. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.523 |
hmg20a | hmg20b | ENSPREP00000018594 | ENSPREP00000012358 | High mobility group 20A. | High mobility group 20B. | 0.840 |
hmg20a | kdm1a | ENSPREP00000018594 | ENSPREP00000006670 | High mobility group 20A. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.871 |
hmg20a | phf21a | ENSPREP00000018594 | ENSPREP00000030809 | High mobility group 20A. | PHD finger protein 21Ab. | 0.789 |
hmg20a | rcor1 | ENSPREP00000018594 | ENSPREP00000006226 | High mobility group 20A. | REST corepressor 1. | 0.621 |
hmg20a | rcor2 | ENSPREP00000018594 | ENSPREP00000001173 | High mobility group 20A. | REST corepressor 2. | 0.621 |
hmg20a | rcor3 | ENSPREP00000018594 | ENSPREP00000033517 | High mobility group 20A. | REST corepressor 3. | 0.621 |
hmg20b | LOC103458631 | ENSPREP00000012358 | ENSPREP00000002417 | High mobility group 20B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.682 |
hmg20b | hmg20a | ENSPREP00000012358 | ENSPREP00000018594 | High mobility group 20B. | High mobility group 20A. | 0.840 |
hmg20b | kdm1a | ENSPREP00000012358 | ENSPREP00000006670 | High mobility group 20B. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.971 |