lmnb1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lmnb1

Lamin B1; Belongs to the intermediate filament family. (584 aa)

Predicted Functional Partners:

casp6

0.972

lmnb2

0.906

lemd3

0.842

sun2

0.809

banf1

0.781

LOC103477399

0.781

LOC103459576

0.752

nup153

0.705

sun1

0.666

ENSPREP00000010727

0.653

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000010727	lmnb1	ENSPREP00000010727	ENSPREP00000006678	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Lamin B1; Belongs to the intermediate filament family.	0.653
ENSPREP00000010727	lmnb2	ENSPREP00000010727	ENSPREP00000030057	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	Lamin B2; Belongs to the intermediate filament family.	0.653
LOC103459576	LOC103477399	ENSPREP00000018115	ENSPREP00000019489	Uncharacterized protein.	Uncharacterized protein.	0.855
LOC103459576	banf1	ENSPREP00000018115	ENSPREP00000017597	Uncharacterized protein.	Barrier to autointegration factor 1.	0.855
LOC103459576	lemd3	ENSPREP00000018115	ENSPREP00000026156	Uncharacterized protein.	LEM domain containing 3.	0.812
LOC103459576	lmnb1	ENSPREP00000018115	ENSPREP00000006678	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.752
LOC103459576	lmnb2	ENSPREP00000018115	ENSPREP00000030057	Uncharacterized protein.	Lamin B2; Belongs to the intermediate filament family.	0.752
LOC103477399	LOC103459576	ENSPREP00000019489	ENSPREP00000018115	Uncharacterized protein.	Uncharacterized protein.	0.855
LOC103477399	lemd3	ENSPREP00000019489	ENSPREP00000026156	Uncharacterized protein.	LEM domain containing 3.	0.896
LOC103477399	lmnb1	ENSPREP00000019489	ENSPREP00000006678	Uncharacterized protein.	Lamin B1; Belongs to the intermediate filament family.	0.781
LOC103477399	lmnb2	ENSPREP00000019489	ENSPREP00000030057	Uncharacterized protein.	Lamin B2; Belongs to the intermediate filament family.	0.796
banf1	LOC103459576	ENSPREP00000017597	ENSPREP00000018115	Barrier to autointegration factor 1.	Uncharacterized protein.	0.855
banf1	lemd3	ENSPREP00000017597	ENSPREP00000026156	Barrier to autointegration factor 1.	LEM domain containing 3.	0.896
banf1	lmnb1	ENSPREP00000017597	ENSPREP00000006678	Barrier to autointegration factor 1.	Lamin B1; Belongs to the intermediate filament family.	0.781
banf1	lmnb2	ENSPREP00000017597	ENSPREP00000030057	Barrier to autointegration factor 1.	Lamin B2; Belongs to the intermediate filament family.	0.796
casp6	lmnb1	ENSPREP00000003415	ENSPREP00000006678	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Lamin B1; Belongs to the intermediate filament family.	0.972
casp6	lmnb2	ENSPREP00000003415	ENSPREP00000030057	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Lamin B2; Belongs to the intermediate filament family.	0.972
lemd3	LOC103459576	ENSPREP00000026156	ENSPREP00000018115	LEM domain containing 3.	Uncharacterized protein.	0.812
lemd3	LOC103477399	ENSPREP00000026156	ENSPREP00000019489	LEM domain containing 3.	Uncharacterized protein.	0.896
lemd3	banf1	ENSPREP00000026156	ENSPREP00000017597	LEM domain containing 3.	Barrier to autointegration factor 1.	0.896