Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KCTD1Potassium channel tetramerization domain containing 1. (342 aa)    
Predicted Functional Partners:
tfap2e
Transcription factor AP-2 epsilon.
   
 0.698
tfap2d
Transcription factor AP-2 delta (activating enhancer binding protein 2 delta).
   
 0.698
tfap2b
Transcription factor AP-2 beta.
   
 0.698
tfap2c
Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma).
   
 0.698
tfap2a
Transcription factor AP-2 alpha.
   
 0.698
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.688
LOC103468487
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.688
kctd2
Potassium channel tetramerization domain containing 2.
    
 
 0.685
kctd5
Potassium channel tetramerization domain containing 5a.
    
 0.628
yeats4
YEATS domain containing 4.
      
 0.603
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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