STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Usp42USP domain-containing protein; Belongs to the peptidase C19 family. (219 aa)    
Predicted Functional Partners:
suds3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.789
rce1
Ras converting CAAX endopeptidase 1a.
     
 0.662
ENSPREP00000010801
Uncharacterized protein.
     
 0.662
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
  0.636
ifih1
Interferon induced with helicase C domain 1.
     
 0.624
CDC25B
Cell division cycle 25B.
    
 0.615
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
    
 0.591
ythdf2
YTH N(6)-methyladenosine RNA binding protein 2.
      
 0.580
ube2w
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.578
dhx33
DEAH (Asp-Glu-Ala-His) box polypeptide 33.
    
 
 0.571
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.