Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dlx3Distal-less homeobox 3b. (281 aa)    
Predicted Functional Partners:
meis1
Meis homeobox 1 b.
    
 
 0.761
meis2
Meis homeobox 2a.
    
 
 0.761
ENSPREP00000032134
Forkhead box N1.
    
 
 0.708
ENSPREP00000011029
Uncharacterized protein.
    
 
 0.671
tradd
Tnfrsf1a-associated via death domain.
      
 0.670
LOC103466878
Keratin 5; Belongs to the intermediate filament family.
   
  
 0.631
lef1
Lymphoid enhancer-binding factor 1.
    
 0.627
LOC103476521
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.606
rab28
Uncharacterized protein.
      
 0.604
itgb6
Integrin beta; Belongs to the integrin beta chain family.
      
 0.601
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.