STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdprPyruvate dehydrogenase phosphatase regulatory subunit. (892 aa)    
Predicted Functional Partners:
gldc
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.922
ENSPREP00000006862
Uncharacterized protein.
  
 0.875
gcsh
Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.
  
 0.875
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.858
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.849
LOC103466019
Putative pyruvate dehydrogenase phosphatase isoenzyme 2.
  
 0.836
ENSPREP00000022378
Si:ch211-15p9.2.
  
 0.836
pdp1
Pyruvate dehyrogenase phosphatase catalytic subunit 1.
  
 0.836
nudcd1
NudC domain containing 1.
    
   0.835
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 0.735
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.