Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem267Transmembrane protein 267. (247 aa)    
Predicted Functional Partners:
WDR70
WD repeat domain 70.
      
 0.638
ENSPREP00000007333
Haloacid dehalogenase-like hydrolase domain containing 2.
      
 0.597
LOC103473567
Claudin 23a.
      
 0.532
nadk2
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
      
 0.530
carm1
Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
      
 0.519
rchy1
Uncharacterized protein.
      
 0.498
prxl2c
Peroxiredoxin like 2C.
      
 0.474
amacr
Alpha-methylacyl-CoA racemase.
      
 0.470
paip1
Poly(A) binding protein interacting protein 1.
      
 0.468
LOC103470087
Uncharacterized protein.
      
 0.440
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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