Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC103475987Embryonal Fyn-associated substrate. (970 aa)    
Predicted Functional Partners:
mysm1
Myb-like, SWIRM and MPN domains 1.
   
 0.782
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.733
crk
CRK proto-oncogene, adaptor protein.
    
 0.733
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.733
ptk2
Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.667
LOC103475221
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.667
LOC103472469
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.667
LOC103457606
Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.667
rai14
Retinoic acid induced 14.
    
 0.666
LOC103464969
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.664
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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