MOK protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

MOK

MOK protein kinase. (508 aa)

Predicted Functional Partners:

myrf

0.778

cdc6

0.719

mcm2

0.714

cdt1

0.711

mcm4

0.711

Mcm5

0.711

mcm3

0.711

orc3

0.711

mcm6

0.711

orc2

0.711

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MOK	Mcm5	ENSPREP00000006961	ENSPREP00000022230	MOK protein kinase.	Uncharacterized protein.	0.711
MOK	cdc6	ENSPREP00000006961	ENSPREP00000032222	MOK protein kinase.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.719
MOK	cdt1	ENSPREP00000006961	ENSPREP00000011428	MOK protein kinase.	Chromatin licensing and DNA replication factor 1.	0.711
MOK	mcm2	ENSPREP00000006961	ENSPREP00000033565	MOK protein kinase.	DNA helicase; Belongs to the MCM family.	0.714
MOK	mcm3	ENSPREP00000006961	ENSPREP00000028616	MOK protein kinase.	DNA helicase; Belongs to the MCM family.	0.711
MOK	mcm4	ENSPREP00000006961	ENSPREP00000012626	MOK protein kinase.	DNA helicase; Belongs to the MCM family.	0.711
MOK	mcm6	ENSPREP00000006961	ENSPREP00000031351	MOK protein kinase.	DNA helicase; Belongs to the MCM family.	0.711
MOK	myrf	ENSPREP00000006961	ENSPREP00000017004	MOK protein kinase.	Myelin regulatory factor.	0.778
MOK	orc2	ENSPREP00000006961	ENSPREP00000031604	MOK protein kinase.	Origin recognition complex, subunit 2.	0.711
MOK	orc3	ENSPREP00000006961	ENSPREP00000030895	MOK protein kinase.	Origin recognition complex, subunit 3.	0.711
Mcm5	MOK	ENSPREP00000022230	ENSPREP00000006961	Uncharacterized protein.	MOK protein kinase.	0.711
Mcm5	cdc6	ENSPREP00000022230	ENSPREP00000032222	Uncharacterized protein.	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	0.995
Mcm5	cdt1	ENSPREP00000022230	ENSPREP00000011428	Uncharacterized protein.	Chromatin licensing and DNA replication factor 1.	0.999
Mcm5	mcm2	ENSPREP00000022230	ENSPREP00000033565	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.999
Mcm5	mcm3	ENSPREP00000022230	ENSPREP00000028616	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.999
Mcm5	mcm4	ENSPREP00000022230	ENSPREP00000012626	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.999
Mcm5	mcm6	ENSPREP00000022230	ENSPREP00000031351	Uncharacterized protein.	DNA helicase; Belongs to the MCM family.	0.999
Mcm5	orc2	ENSPREP00000022230	ENSPREP00000031604	Uncharacterized protein.	Origin recognition complex, subunit 2.	0.994
Mcm5	orc3	ENSPREP00000022230	ENSPREP00000030895	Uncharacterized protein.	Origin recognition complex, subunit 3.	0.994
cdc6	MOK	ENSPREP00000032222	ENSPREP00000006961	Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.	MOK protein kinase.	0.719