STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EIF4E3-2Eukaryotic translation initiation factor 4E family member 3; Belongs to the eukaryotic initiation factor 4E family. (235 aa)    
Predicted Functional Partners:
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.853
eif4g3
Eukaryotic translation initiation factor 4 gamma, 3a.
   
 0.832
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 0.815
LOC103479599
Uncharacterized protein.
   
 0.806
ENSPREP00000004501
Uncharacterized protein.
   
 0.806
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
   
 0.806
LOC103465618
Eukaryotic translation initiation factor 4, gamma 2b.
   
 0.801
eif4g2
Eukaryotic translation initiation factor 4, gamma 2a.
   
 0.801
LOC103480125
Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.
   
 0.756
eif4a2
Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family.
   
 0.756
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.