STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (335 aa)    
Predicted Functional Partners:
aqp8
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
0.766
LOC103476302
Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
     
 0.742
arrdc3
Arrestin domain containing 3a.
      
 0.650
LOC103473229
Occludin a.
   
 
 0.613
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
 
 0.608
LOC103470457
Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.606
LOC103478150
Aquaporin 10a; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.595
LOC103478152
Aquaporin 10a; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.595
aqp9
Aquaporin 9b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
  
0.592
LOC103477848
Apolipoprotein Eb.
      
 0.585
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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