STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103471208Nedd4 family interacting protein 1. (223 aa)    
Predicted Functional Partners:
trip12
Thyroid hormone receptor interactor 12.
      
 0.563
nedd4
E3 ubiquitin-protein ligase.
    
 
 0.502
nedd4l
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.502
SLC11A2
Solute carrier family 11 member 2.
   
 
 0.491
LOC103467973
Solute carrier family 11 member 2.
   
 
 0.491
wwp2
E3 ubiquitin-protein ligase.
    
 
 0.478
wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
 
 0.478
ndufa6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
      
 0.468
itch
E3 ubiquitin-protein ligase.
    
 
 0.420
LOC103464828
E3 ubiquitin-protein ligase.
    
 
 0.420
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.