STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Kcnj1Potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6. (374 aa)    
Predicted Functional Partners:
ENSPREP00000004336
Uncharacterized protein.
   
 
  0.595
LOC103481591
Potassium inwardly-rectifying channel, subfamily J, member 16.
   
 
  0.595
fam131c
Family with sequence similarity 131 member C.
      
 0.571
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.563
miox
Myo-inositol oxygenase.
   
  
 0.541
LOC103467347
Solute carrier family 26 member 10.
   
  
 0.422
slc35b1
Solute carrier family 35 member B1.
      
 0.418
LOC103460789
ATP-binding cassette, sub-family C (CFTR/MRP), member 9.
    
 0.408
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
    
 0.408
cipc
CLOCK-interacting pacemaker a.
   
  
 0.401
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.