STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103473171Sprouty related EVH1 domain containing 2a. (409 aa)    
Predicted Functional Partners:
nf1
Neurofibromin 1b.
    
 0.830
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.695
ofd1
OFD1 centriole and centriolar satellite protein.
    
 
 0.585
sqstm1
Sequestosome 1.
    
   0.585
CSDE1
Cold shock domain containing E1, RNA-binding.
   
 0.561
LOC103469088
Zgc:55558.
   
 0.561
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.561
hras
HRas proto-oncogene, GTPase a.
   
 0.561
ENSPREP00000015948
Fibroblast growth factor receptor like 1a.
     
 0.555
FGFRL1
Fibroblast growth factor receptor like 1.
     
 0.555
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.