tirap protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

tirap

Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (231 aa)

Predicted Functional Partners:

myd88

0.989

traf6

0.980

irak4

0.966

LOC103480941

0.949

tlr2

0.949

LOC103477637

0.941

ENSPREP00000024840

0.899

tollip

0.865

tep1

0.834

yipf4

0.681

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000024840	LOC103477637	ENSPREP00000024840	ENSPREP00000028747	TIR domain-containing protein.	Toll-like receptor 18.	0.723
ENSPREP00000024840	LOC103480941	ENSPREP00000024840	ENSPREP00000008821	TIR domain-containing protein.	TIR domain-containing protein.	0.723
ENSPREP00000024840	irak4	ENSPREP00000024840	ENSPREP00000014585	TIR domain-containing protein.	Interleukin-1 receptor-associated kinase 4.	0.717
ENSPREP00000024840	myd88	ENSPREP00000024840	ENSPREP00000031341	TIR domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.988
ENSPREP00000024840	tirap	ENSPREP00000024840	ENSPREP00000007146	TIR domain-containing protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.899
ENSPREP00000024840	tlr2	ENSPREP00000024840	ENSPREP00000011774	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.723
ENSPREP00000024840	tollip	ENSPREP00000024840	ENSPREP00000003032	TIR domain-containing protein.	Toll interacting protein.	0.660
ENSPREP00000024840	traf6	ENSPREP00000024840	ENSPREP00000005082	TIR domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.990
LOC103477637	ENSPREP00000024840	ENSPREP00000028747	ENSPREP00000024840	Toll-like receptor 18.	TIR domain-containing protein.	0.723
LOC103477637	LOC103480941	ENSPREP00000028747	ENSPREP00000008821	Toll-like receptor 18.	TIR domain-containing protein.	0.900
LOC103477637	myd88	ENSPREP00000028747	ENSPREP00000031341	Toll-like receptor 18.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.952
LOC103477637	tirap	ENSPREP00000028747	ENSPREP00000007146	Toll-like receptor 18.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.941
LOC103477637	tlr2	ENSPREP00000028747	ENSPREP00000011774	Toll-like receptor 18.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
LOC103477637	tollip	ENSPREP00000028747	ENSPREP00000003032	Toll-like receptor 18.	Toll interacting protein.	0.925
LOC103477637	traf6	ENSPREP00000028747	ENSPREP00000005082	Toll-like receptor 18.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.407
LOC103480941	ENSPREP00000024840	ENSPREP00000008821	ENSPREP00000024840	TIR domain-containing protein.	TIR domain-containing protein.	0.723
LOC103480941	LOC103477637	ENSPREP00000008821	ENSPREP00000028747	TIR domain-containing protein.	Toll-like receptor 18.	0.900
LOC103480941	irak4	ENSPREP00000008821	ENSPREP00000014585	TIR domain-containing protein.	Interleukin-1 receptor-associated kinase 4.	0.452
LOC103480941	myd88	ENSPREP00000008821	ENSPREP00000031341	TIR domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.977
LOC103480941	tirap	ENSPREP00000008821	ENSPREP00000007146	TIR domain-containing protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.949