Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sytl1Synaptotagmin-like 1. (532 aa)    
Predicted Functional Partners:
RAB27B
RAB27B, member RAS oncogene family.
   
 0.842
LOC103469909
Uncharacterized protein.
   
 0.815
ENSPREP00000001350
Uncharacterized protein.
   
 0.812
rab27a
RAB27A, member RAS oncogene family.
   
 0.812
stxbp2
Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.608
LOC103481063
Melanophilin a.
     
 0.594
tbc1d10b
TBC1 domain family, member 10b.
     
  0.563
LOC103470602
TBC1 domain family, member 10Aa.
     
  0.563
tbc1d10a
TBC1 domain family, member 10Ab.
     
  0.563
ENSPREP00000009513
t-SNARE coiled-coil homology domain-containing protein.
    
 0.539
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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