Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
spdyaSpeedy/RINGO cell cycle regulator family member A. (306 aa)    
Predicted Functional Partners:
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.911
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
    
 0.911
appl1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
 0.748
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
   
 
 0.748
LOC103457075
Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.453
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.453
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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