STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrk3Tyrosine-protein kinase receptor. (815 aa)    
Predicted Functional Partners:
ENSPREP00000025003
Uncharacterized protein.
 
      0.844
bdnf
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
   
 0.724
LOC103467432
Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.
    
 0.721
ENSPREP00000007409
NGF domain-containing protein; Belongs to the NGF-beta family.
    
 0.698
ntf3
Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family.
    
 0.690
tmem104
Transmembrane protein 104.
      
 0.646
sytl5
Synaptotagmin-like 5.
      
 0.646
LOC103463439
Protein tyrosine phosphatase receptor type Sa.
   
 0.644
LOC103479283
Protein tyrosine phosphatase receptor type Sa.
   
 0.644
LOC103468988
NGF domain-containing protein; Belongs to the NGF-beta family.
    
 0.624
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.