STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prkceProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (678 aa)    
Predicted Functional Partners:
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.934
hras
HRas proto-oncogene, GTPase a.
   
 0.934
LOC103478268
FERM domain-containing protein.
   
  0.931
EZR
Ezrin b.
   
  0.931
LOC103458206
Ezrin a.
   
  0.931
RDX
Radixin.
   
  0.931
msn
Moesin a.
   
  0.931
LOC103468146
RAS related.
   
 0.922
rras2
RAS related 2.
   
 0.922
mras
Muscle RAS oncogene homolog.
   
 0.921
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.