STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103481539SIX homeobox 3b. (277 aa)    
Predicted Functional Partners:
pax6
Paired box 6b.
   
 
 0.677
lhx2
LIM homeobox 2b.
   
  
 0.633
otx2
Orthodenticle homeobox 2b.
   
 
 0.566
rax
Retinal homeobox gene 3.
      
 0.532
VSX2
Visual system homeobox 2.
   
  
 0.515
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
   
  
 0.490
ENSPREP00000014560
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 
 0.489
eya4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 
 0.489
LOC103464861
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 
 0.489
eya1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 
 0.489
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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