STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hckTyrosine-protein kinase. (500 aa)    
Predicted Functional Partners:
LOC103457799
Uncharacterized protein.
   
 0.740
grb2
Growth factor receptor-bound protein 2b.
   
 0.717
syk
Tyrosine-protein kinase.
   
 0.707
LOC103468233
Tyrosine-protein kinase.
   
 0.697
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.691
ptprc
Protein tyrosine phosphatase receptor type C.
   
 0.678
ENSPREP00000004218
Docking protein 2.
   
 0.662
pag1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.651
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.643
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.643
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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