Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSPREP00000007382USP domain-containing protein; Belongs to the peptidase C19 family. (78 aa)    
Predicted Functional Partners:
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.566
trip12
Thyroid hormone receptor interactor 12.
    
 
 0.549
mrps9
Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.521
mrpl3
Mitochondrial ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.498
mrpl11
Mitochondrial ribosomal protein L11.
   
 
 0.494
mrpl4
Mitochondrial ribosomal protein L4.
   
 
 0.492
mrpl24
Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.
   
 
 0.485
rps18
Ribosomal protein S18; Belongs to the universal ribosomal protein uS13 family.
   
 
 0.478
RPS20
Ribosomal protein S20.
   
 
 0.471
mrps16
Mitochondrial ribosomal protein S16.
   
 
 0.463
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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