STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LOC103469267Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (320 aa)    
Predicted Functional Partners:
LOC103459892
Calcium/calmodulin-dependent protein kinase II alpha.
   
 
 0.737
LOC103469495
Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2.
   
 
 0.737
camk2b
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
   
 
 0.737
LOC103480087
Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily.
   
 
 0.737
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
 0.735
LOC103470494
Uncharacterized protein.
   
 0.735
LOC103464081
Calcium channel, voltage-dependent, R type, alpha 1E subunit a.
   
 
 0.732
LOC103472852
Calcium channel, voltage-dependent, gamma subunit 8a.
  
 
 
0.721
LOC103478057
Calcium channel, voltage-dependent, gamma subunit 8b.
  
 
 
0.721
ppp2r5b
Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.
     
 0.716
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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