STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000007450Uncharacterized protein. (511 aa)    
Predicted Functional Partners:
ENSPREP00000015870
Uncharacterized protein.
 
 
 0.965
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.959
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.940
ENSPREP00000008107
Intersectin 1 (SH3 domain protein).
 
 
 0.935
ap4b1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.899
LOC103476383
AP complex subunit beta.
    
 0.899
ap1b1
AP complex subunit beta.
    
 0.899
LOC103460570
Growth arrest-specific 7a.
   
 0.897
gas7
Growth arrest specific 7.
   
 0.897
fcho1
FCH domain only 1.
   
 0.895
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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