STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103481546GTP cyclohydrolase 2. (236 aa)    
Predicted Functional Partners:
gchfr
GTP cyclohydrolase I feedback regulator.
    
 0.985
gch1
GTP cyclohydrolase 1.
  
  
 
0.901
LOC103463453
Alkaline phosphatase.
     
  0.900
LOC103463511
Alkaline phosphatase, intestinal, tandem duplicate 2; Belongs to the alkaline phosphatase family.
     
  0.900
LOC103474915
Alkaline phosphatase.
     
  0.900
alpl
Alkaline phosphatase.
     
  0.900
pts
6-pyruvoyl tetrahydrobiopterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
  
 
 0.895
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
    
 0.860
LOC103481041
Guanylate cyclase.
     
 0.836
LOC103468453
Guanylate cyclase.
     
 0.836
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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