STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
slf1SMC5-SMC6 complex localization factor 1. (880 aa)    
Predicted Functional Partners:
rad18
RAD18 E3 ubiquitin protein ligase.
   
 
 0.981
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.954
bard1
BRCA1 associated RING domain 1.
   
 0.944
nbn
Nibrin.
    
 0.935
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.928
rad17
RAD17 checkpoint clamp loader component.
  
 0.925
rad1
RAD1 homolog (S. pombe).
    
 0.920
atm
Non-specific serine/threonine protein kinase.
   
 0.919
smc5
Structural maintenance of chromosomes 5.
   
 
 0.916
Fam21c
Uncharacterized protein.
    
 
 0.913
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.