STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flt4Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1390 aa)    
Predicted Functional Partners:
vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.957
grb2
Growth factor receptor-bound protein 2b.
   
 0.885
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.883
Pgf
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.860
LOC103477155
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
   
 0.848
pik3r3
Uncharacterized protein.
    
 0.846
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.846
pik3r1
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.846
vegfa
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
    
 0.845
Kitlg
Kit ligand a.
    
 0.842
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.