STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smpdl3bAcid sphingomyelinase-like phosphodiesterase. (460 aa)    
Predicted Functional Partners:
tmem259
Transmembrane protein 259.
      
 0.758
cachd1
Cache domain containing 1.
      
 0.729
fam131c
Family with sequence similarity 131 member C.
      
 0.727
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
      
 0.658
ENSPREP00000014352
XK-related protein.
 
    
 0.654
selenoi
Selenoprotein I; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
      
 0.648
sh3rf1
SH3 domain containing ring finger 1.
      
 0.607
actr6
Actin related protein 6; Belongs to the actin family.
      
 0.603
mrps11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
      
 0.602
Mrpl35
Mitochondrial ribosomal protein L35.
      
 0.602
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.