STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxo42F-box protein 42. (701 aa)    
Predicted Functional Partners:
cul1
Cullin 1b; Belongs to the cullin family.
    
 
 0.780
fbxo47
F-box domain-containing protein.
      
 0.560
chek2
Checkpoint kinase 2.
   
 
 0.554
LOC103479463
Sirtuin 6.
      
 0.549
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 
 0.547
LOC103479391
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 
 0.530
LOC103474461
Cullin 3; Belongs to the cullin family.
    
 
 0.530
drg1
Developmentally regulated GTP binding protein 1.
    
   0.476
ptpn21
Protein tyrosine phosphatase non-receptor type 21.
      
 0.468
pole2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
    
 
 0.462
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.