STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)    
Predicted Functional Partners:
rad18
RAD18 E3 ubiquitin protein ligase.
    
 0.936
trip12
Thyroid hormone receptor interactor 12.
    
 0.900
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.893
LOC103471296
E3 ubiquitin protein ligase.
    
 0.867
rnf40
E3 ubiquitin protein ligase.
    
 0.867
rps27a
Ribosomal protein S27a.
    
 0.860
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.832
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.819
LOC103464541
Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.816
uba6
Ubiquitin like modifier activating enzyme 6.
   
 0.816
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.