STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
atf2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (467 aa)    
Predicted Functional Partners:
ENSPREP00000002835
Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.
   
 0.893
LOC103471253
Mitogen-activated protein kinase.
   
 0.881
ENSPREP00000020034
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.867
c-fos
V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.
    
 0.821
LOC103457597
Jun dimerization protein 2.
    
 
 0.798
fosl2
Fos-like antigen 2.
    
 0.774
mapk10
Mitogen-activated protein kinase.
   
 0.735
LOC103476945
Mitogen-activated protein kinase.
   
 0.735
mapk8
Mitogen-activated protein kinase.
   
 0.735
LOC103464508
JunB proto-oncogene, AP-1 transcription factor subunit a.
   
 0.730
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.