STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aff4AF4/FMR2 family, member 4. (1106 aa)    
Predicted Functional Partners:
Cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase).
    
 0.999
eaf1
EAF domain-containing protein.
    
 0.999
eaf2
ELL associated factor 2.
    
 0.997
ENSPREP00000012074
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.995
ccnt2
Cyclin T2; Belongs to the cyclin family.
   
 0.995
mllt3
MLLT3 super elongation complex subunit.
    
 0.994
mllt1
MLLT1 super elongation complex subunit a.
    
 0.994
ell2
Elongation factor, RNA polymerase II, 2.
    
 0.993
ell
Elongation factor RNA polymerase II.
    
 0.990
LOC103462177
Uncharacterized protein.
    
 0.988
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.