STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aff4AF4/FMR2 family, member 4. (1106 aa)    
Predicted Functional Partners:
Cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase).
    
 0.984
ENSPREP00000012074
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.961
ccnt2
Cyclin T2; Belongs to the cyclin family.
   
 0.961
eaf2
ELL associated factor 2.
    
 0.921
ell2
Elongation factor, RNA polymerase II, 2.
   
 0.907
eaf1
EAF domain-containing protein.
    
 0.897
ell
Elongation factor RNA polymerase II.
   
 0.883
mllt3
MLLT3 super elongation complex subunit.
    
 0.872
mllt1
MLLT1 super elongation complex subunit a.
    
 0.872
LOC103462177
Uncharacterized protein.
   
 0.859
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.