STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
topbp1DNA topoisomerase II binding protein 1. (1453 aa)    
Predicted Functional Partners:
rhno1
Si:ch73-352p4.5.
    
 0.997
ticrr
Treslin_N domain-containing protein.
   
 
 0.996
atrip
Uncharacterized protein.
    
 0.996
brip1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.995
brca1
Uncharacterized protein.
   
 0.995
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.994
bard1
BRCA1 associated RING domain 1.
   
 0.993
CLSPN
Claspin.
   
 0.991
nbn
Nibrin.
    
 0.983
e2f1
E2F transcription factor 1.
    
 
 0.979
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.