STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000007849IRS-type PTB domain-containing protein. (458 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.679
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.531
LOC103478660
Ankyrin repeat domain 50-like.
      
 0.531
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.530
crk
CRK proto-oncogene, adaptor protein.
    
 0.530
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.530
wdr11
WD repeat domain 11.
      
 0.526
dqx1
DEAQ box RNA-dependent ATPase 1.
      
 0.524
ENSPREP00000028962
Zgc:123010.
      
 0.524
ENSPREP00000011029
Uncharacterized protein.
      
 0.522
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.