STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000007849IRS-type PTB domain-containing protein. (458 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.778
pomk
Protein O-mannose kinase.
      
 0.654
mios
Missing oocyte, meiosis regulator, homolog (Drosophila).
    
 
 0.621
tpp2
Tripeptidyl peptidase 2.
    
 
 0.599
ENSPREP00000009325
GRB2 related adaptor protein b.
    
 0.538
ENSPREP00000009358
Uncharacterized protein.
    
 0.538
LOC103469145
GRB2 related adaptor protein a.
    
 0.538
ENSPREP00000014792
Uncharacterized protein.
      
 0.525
fbxw11
F-box and WD repeat domain containing 11a.
      
 0.513
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.511
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.