STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103457483Otoferlin a. (1904 aa)    
Predicted Functional Partners:
get1
Guided entry of tail-anchored proteins factor 1.
     
 0.590
camlg
Calcium modulating ligand.
     
 0.580
get3
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
     
 0.530
ENSPREP00000002501
Vesicle-associated membrane protein 2.
     
 0.510
ENSPREP00000016345
Zgc:92912.
     
 0.510
fbxl6
F-box domain-containing protein.
   
  
 0.481
ncbp3
Nuclear cap binding subunit 3.
      
 0.475
mllt3
MLLT3 super elongation complex subunit.
      
 0.475
usp37
Ubiquitin carboxyl-terminal hydrolase.
      
 0.473
srcap
Snf2-related CREBBP activator protein.
      
 0.473
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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