srebf1 protein (Poecilia reticulata) - STRING interaction network

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Score

srebf1

Sterol regulatory element binding transcription factor 1. (1207 aa)

Predicted Functional Partners:

fasn

0.923

scap

0.916

kpnb1

0.850

mbtps2

0.845

PPARG

0.794

mbtps1

0.784

NPC1L1

0.772

npc1

0.772

LOC103464091

0.751

crebbp

0.751

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	PPARG	ENSPREP00000000408	ENSPREP00000009292	CREB binding protein a.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.869
LOC103464091	crebbp	ENSPREP00000000408	ENSPREP00000011232	CREB binding protein a.	CREB binding protein b.	0.901
LOC103464091	srebf1	ENSPREP00000000408	ENSPREP00000007886	CREB binding protein a.	Sterol regulatory element binding transcription factor 1.	0.751
NPC1L1	mbtps1	ENSPREP00000014842	ENSPREP00000000957	NPC1 like intracellular cholesterol transporter 1.	Membrane-bound transcription factor peptidase, site 1.	0.629
NPC1L1	srebf1	ENSPREP00000014842	ENSPREP00000007886	NPC1 like intracellular cholesterol transporter 1.	Sterol regulatory element binding transcription factor 1.	0.772
PPARG	LOC103464091	ENSPREP00000009292	ENSPREP00000000408	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	CREB binding protein a.	0.869
PPARG	crebbp	ENSPREP00000009292	ENSPREP00000011232	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	CREB binding protein b.	0.869
PPARG	fasn	ENSPREP00000009292	ENSPREP00000005709	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Coiled-coil domain containing 57.	0.613
PPARG	srebf1	ENSPREP00000009292	ENSPREP00000007886	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Sterol regulatory element binding transcription factor 1.	0.794
crebbp	LOC103464091	ENSPREP00000011232	ENSPREP00000000408	CREB binding protein b.	CREB binding protein a.	0.901
crebbp	PPARG	ENSPREP00000011232	ENSPREP00000009292	CREB binding protein b.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.869
crebbp	srebf1	ENSPREP00000011232	ENSPREP00000007886	CREB binding protein b.	Sterol regulatory element binding transcription factor 1.	0.751
fasn	PPARG	ENSPREP00000005709	ENSPREP00000009292	Coiled-coil domain containing 57.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.613
fasn	mbtps1	ENSPREP00000005709	ENSPREP00000000957	Coiled-coil domain containing 57.	Membrane-bound transcription factor peptidase, site 1.	0.408
fasn	scap	ENSPREP00000005709	ENSPREP00000029624	Coiled-coil domain containing 57.	SREBF chaperone.	0.411
fasn	srebf1	ENSPREP00000005709	ENSPREP00000007886	Coiled-coil domain containing 57.	Sterol regulatory element binding transcription factor 1.	0.923
kpnb1	srebf1	ENSPREP00000018146	ENSPREP00000007886	Karyopherin (importin) beta 1.	Sterol regulatory element binding transcription factor 1.	0.850
mbtps1	NPC1L1	ENSPREP00000000957	ENSPREP00000014842	Membrane-bound transcription factor peptidase, site 1.	NPC1 like intracellular cholesterol transporter 1.	0.629
mbtps1	fasn	ENSPREP00000000957	ENSPREP00000005709	Membrane-bound transcription factor peptidase, site 1.	Coiled-coil domain containing 57.	0.408
mbtps1	mbtps2	ENSPREP00000000957	ENSPREP00000033833	Membrane-bound transcription factor peptidase, site 1.	Membrane-bound transcription factor peptidase, site 2.	0.892