Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
HSD17B7Hydroxysteroid 17-beta dehydrogenase 7. (319 aa)    
Predicted Functional Partners:
nsdhl
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 0.987
msmo1
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 0.981
dhcr24
24-dehydrocholesterol reductase.
   
 
 0.961
ebp
EBP cholestenol delta-isomerase.
   
 
 0.950
LOC103472946
Hydroxysteroid (17-beta) dehydrogenase 8.
     
 0.948
dhrs11
Dehydrogenase/reductase (SDR family) member 11a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.937
LOC103474142
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.937
aromatase
Uncharacterized protein; Belongs to the cytochrome P450 family.
    
 0.935
LOC103462065
Cytochrome P450, family 19, subfamily A, polypeptide 1a; Belongs to the cytochrome P450 family.
    
 0.935
LOC103462728
Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.932
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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