brd4 protein (Poecilia reticulata) - STRING interaction network

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Score

brd4

Bromodomain containing 4. (1560 aa)

Predicted Functional Partners:

Cdk9

0.782

nsd3

0.672

jmjd6

0.670

taf7l

0.645

yeats4

0.638

LOC103475759

0.636

dmap1

0.633

ENSPREP00000012507

0.630

tp53

0.629

ruvbl2

0.621

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cdk9	brd4	ENSPREP00000011203	ENSPREP00000007965	Cyclin-dependent kinase 9 (CDC2-related kinase).	Bromodomain containing 4.	0.782
Cdk9	tp53	ENSPREP00000011203	ENSPREP00000019676	Cyclin-dependent kinase 9 (CDC2-related kinase).	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.938
Cdk9	yeats4	ENSPREP00000011203	ENSPREP00000006340	Cyclin-dependent kinase 9 (CDC2-related kinase).	YEATS domain containing 4.	0.636
ENSPREP00000012507	LOC103475759	ENSPREP00000012507	ENSPREP00000032525	HARE-HTH domain-containing protein.	Transcription initiation factor TFIID subunit.	0.533
ENSPREP00000012507	brd4	ENSPREP00000012507	ENSPREP00000007965	HARE-HTH domain-containing protein.	Bromodomain containing 4.	0.630
ENSPREP00000012507	tp53	ENSPREP00000012507	ENSPREP00000019676	HARE-HTH domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.505
LOC103475759	ENSPREP00000012507	ENSPREP00000032525	ENSPREP00000012507	Transcription initiation factor TFIID subunit.	HARE-HTH domain-containing protein.	0.533
LOC103475759	brd4	ENSPREP00000032525	ENSPREP00000007965	Transcription initiation factor TFIID subunit.	Bromodomain containing 4.	0.636
LOC103475759	ruvbl2	ENSPREP00000032525	ENSPREP00000012900	Transcription initiation factor TFIID subunit.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.584
LOC103475759	taf7l	ENSPREP00000032525	ENSPREP00000016738	Transcription initiation factor TFIID subunit.	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
LOC103475759	tp53	ENSPREP00000032525	ENSPREP00000019676	Transcription initiation factor TFIID subunit.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.858
LOC103475759	yeats4	ENSPREP00000032525	ENSPREP00000006340	Transcription initiation factor TFIID subunit.	YEATS domain containing 4.	0.571
brd4	Cdk9	ENSPREP00000007965	ENSPREP00000011203	Bromodomain containing 4.	Cyclin-dependent kinase 9 (CDC2-related kinase).	0.782
brd4	ENSPREP00000012507	ENSPREP00000007965	ENSPREP00000012507	Bromodomain containing 4.	HARE-HTH domain-containing protein.	0.630
brd4	LOC103475759	ENSPREP00000007965	ENSPREP00000032525	Bromodomain containing 4.	Transcription initiation factor TFIID subunit.	0.636
brd4	dmap1	ENSPREP00000007965	ENSPREP00000023811	Bromodomain containing 4.	DNA methyltransferase 1 associated protein 1.	0.633
brd4	jmjd6	ENSPREP00000007965	ENSPREP00000017838	Bromodomain containing 4.	Jumonji domain containing 6, arginine demethylase and lysine hydroxylase.	0.670
brd4	nsd3	ENSPREP00000007965	ENSPREP00000017535	Bromodomain containing 4.	Nuclear receptor binding SET domain protein 3.	0.672
brd4	ruvbl2	ENSPREP00000007965	ENSPREP00000012900	Bromodomain containing 4.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.621
brd4	taf7l	ENSPREP00000007965	ENSPREP00000016738	Bromodomain containing 4.	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.645