Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC103465141Uncharacterized protein. (193 aa)    
Predicted Functional Partners:
ARHGEF2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
   
 0.973
rock2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.972
rock1
Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.972
arhgap5
Rho GTPase activating protein 5.
    
 0.959
daam2
Dishevelled associated activator of morphogenesis 2.
    
 0.959
arhgef11
Rho guanine nucleotide exchange factor (GEF) 11.
   
 0.959
diaph2
Diaphanous-related formin 2.
   
 0.959
ENSPREP00000021285
DH domain-containing protein.
   
 0.959
arhgef1
Rho guanine nucleotide exchange factor (GEF) 1b.
   
 0.959
DIAPH1
Diaphanous related formin 1.
   
 0.959
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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