Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ticrrTreslin_N domain-containing protein. (1692 aa)    
Predicted Functional Partners:
topbp1
DNA topoisomerase II binding protein 1.
   
 
 0.996
dbf4
DBF4 zinc finger.
   
  
 0.872
mtbp
MDM2 binding protein.
   
 0.867
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
  
 0.842
gins4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.818
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.796
ccna1
Cyclin A1; Belongs to the cyclin family.
   
 0.796
fbl
Fibrillarin.
   
 
 0.791
gins3
GINS complex subunit 3.
      
 0.779
fanci
FA complementation group I.
   
 
 0.777
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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