STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
higd2aHIG1 hypoxia inducible domain family, member 2A. (117 aa)    
Predicted Functional Partners:
COX3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
    
 
 0.905
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
    
 
 0.900
LOC103468946
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 
 0.880
LOC103469699
Cytochrome c oxidase subunit 6A, mitochondrial.
   
 
 0.880
LOC103464663
Cytochrome c oxidase assembly factor COX14.
   
  
 0.805
LOC103477149
Cytochrome c oxidase subunit 5B2.
   
 
 0.740
COX5B
Cytochrome c oxidase subunit 5B.
   
 
 0.740
LOC103473152
Uncharacterized protein.
   
 
 0.740
lamtor2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
   
    0.719
LOC103478035
Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
   
 
 0.681
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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