STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (492 aa)    
Predicted Functional Partners:
dld
Dihydrolipoyl dehydrogenase.
 
 0.999
bckdha
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.999
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
 
 0.998
pccb
Propionyl-CoA carboxylase subunit beta.
  
 
 0.979
ivd
Isovaleryl-CoA dehydrogenase.
  
 0.978
ppm1k
Protein phosphatase, Mg2+/Mn2+ dependent, 1K.
    
 0.973
ENSPREP00000003097
Si:ch211-149b19.3.
    
 0.973
pcca
Propionyl-CoA carboxylase subunit alpha.
  
 0.968
acadsb
Acyl-CoA dehydrogenase short/branched chain.
  
 0.957
acads
Acyl-CoA dehydrogenase short chain.
  
 0.957
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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