Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103476019Fibronectin leucine rich transmembrane protein 1. (727 aa)    
Predicted Functional Partners:
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.583
fgf17
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.583
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
     
  0.562
unc5b
Unc-5 netrin receptor B.
    
 0.556
fgf1
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
 0.535
LOC103476521
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
 0.533
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit.
      
 0.520
fgf5
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
     
  0.520
ENSPREP00000006768
Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]
     
 0.520
LOC103471157
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.
      
 0.520
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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