Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BEST3Bestrophin homolog; Forms chloride channels; Belongs to the bestrophin family. (646 aa)    
Predicted Functional Partners:
AXL
AXL receptor tyrosine kinase.
      
 0.485
LOC103479587
Glutamine synthetase.
    
 
 0.470
LOC103463995
Glutamine synthetase.
    
 
 0.470
pelo
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.
 
      0.470
nrip1
Nuclear receptor interacting protein 1b.
      
 0.465
LOC103467277
G protein-coupled receptor 153.
   
  
 0.419
GLIPR1
GLI pathogenesis related 1; Belongs to the CRISP family.
   
  
 0.401
cct2
Chaperonin containing TCP1, subunit 2 (beta).
      
 0.400
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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