LOC103466391 protein (Poecilia reticulata) - STRING interaction network

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LOC103466391

Programmed cell death 4a. (434 aa)

Predicted Functional Partners:

mtap

0.735

LOC103480125

0.713

eif4a2

0.713

fbxw11

0.657

Topors

0.642

eif4a3

0.632

eif3a

0.584

reck

0.581

tet2

0.580

cxxc4

0.556

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103466391	LOC103480125	ENSPREP00000008243	ENSPREP00000005047	Programmed cell death 4a.	Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.	0.713
LOC103466391	Topors	ENSPREP00000008243	ENSPREP00000008624	Programmed cell death 4a.	RING-type domain-containing protein.	0.642
LOC103466391	cxxc4	ENSPREP00000008243	ENSPREP00000008758	Programmed cell death 4a.	CXXC finger 4.	0.556
LOC103466391	eif3a	ENSPREP00000008243	ENSPREP00000002862	Programmed cell death 4a.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.584
LOC103466391	eif4a2	ENSPREP00000008243	ENSPREP00000009555	Programmed cell death 4a.	Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family.	0.713
LOC103466391	eif4a3	ENSPREP00000008243	ENSPREP00000008805	Programmed cell death 4a.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.632
LOC103466391	fbxw11	ENSPREP00000008243	ENSPREP00000002506	Programmed cell death 4a.	F-box and WD repeat domain containing 11a.	0.657
LOC103466391	mtap	ENSPREP00000008243	ENSPREP00000008657	Programmed cell death 4a.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.735
LOC103466391	reck	ENSPREP00000008243	ENSPREP00000019668	Programmed cell death 4a.	Reversion-inducing-cysteine-rich protein with kazal motifs.	0.581
LOC103466391	tet2	ENSPREP00000008243	ENSPREP00000008799	Programmed cell death 4a.	Tet methylcytosine dioxygenase 2.	0.580
LOC103480125	LOC103466391	ENSPREP00000005047	ENSPREP00000008243	Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.	Programmed cell death 4a.	0.713
LOC103480125	eif3a	ENSPREP00000005047	ENSPREP00000002862	Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.903
LOC103480125	eif4a3	ENSPREP00000005047	ENSPREP00000008805	Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.	0.945
Topors	LOC103466391	ENSPREP00000008624	ENSPREP00000008243	RING-type domain-containing protein.	Programmed cell death 4a.	0.642
Topors	cxxc4	ENSPREP00000008624	ENSPREP00000008758	RING-type domain-containing protein.	CXXC finger 4.	0.409
Topors	mtap	ENSPREP00000008624	ENSPREP00000008657	RING-type domain-containing protein.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.680
Topors	tet2	ENSPREP00000008624	ENSPREP00000008799	RING-type domain-containing protein.	Tet methylcytosine dioxygenase 2.	0.580
cxxc4	LOC103466391	ENSPREP00000008758	ENSPREP00000008243	CXXC finger 4.	Programmed cell death 4a.	0.556
cxxc4	Topors	ENSPREP00000008758	ENSPREP00000008624	CXXC finger 4.	RING-type domain-containing protein.	0.409
cxxc4	mtap	ENSPREP00000008758	ENSPREP00000008657	CXXC finger 4.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.546