Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plag1Pleiomorphic adenoma gene 1. (480 aa)    
Predicted Functional Partners:
LOC103458418
Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.
    
 0.674
ENSPREP00000003936
Caudal type homeobox 1a.
    
 
 0.670
eif2ak3
Eukaryotic translation initiation factor 2-alpha kinase 3.
    
 0.661
tcf7
Transcription factor 7.
    
 
 0.614
slitrk6
SLIT and NTRK-like family, member 6.
    
 0.602
htt
Huntingtin.
    
 
 0.589
egf
Epidermal growth factor.
    
 0.580
gpr101
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
    
 0.578
NFIB
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.572
ltv1
LTV1 ribosome biogenesis factor.
     
 0.571
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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