STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103459337Nothepsin; Belongs to the peptidase A1 family. (407 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.761
atp6ap2
ATPase H+ transporting accessory protein 2.
   
 0.732
ctsh
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.628
LOC103472454
Cathepsin S, ortholog 1; Belongs to the peptidase C1 family.
   
 0.620
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.573
LOC103476384
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.555
ENSPREP00000030771
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.555
LOC103461591
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.543
LOC103462835
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.543
ctsb
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.543
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.