prkra protein (Poecilia reticulata) - STRING interaction network

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prkra

Protein kinase, interferon-inducible double stranded RNA dependent activator. (301 aa)

Predicted Functional Partners:

dicer1

0.987

drosha

0.897

LOC103472230

0.888

LOC103477773

0.888

LOC103477771

0.888

ago4

0.888

LOC103477270

0.871

ENSPREP00000011628

0.871

LOC103477355

0.871

LOC103473053

0.832

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000011628	prkra	ENSPREP00000011628	ENSPREP00000008305	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.871
LOC103472230	ago4	ENSPREP00000002849	ENSPREP00000015301	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.552
LOC103472230	dicer1	ENSPREP00000002849	ENSPREP00000017960	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.896
LOC103472230	drosha	ENSPREP00000002849	ENSPREP00000032952	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Drosha ribonuclease III.	0.655
LOC103472230	prkra	ENSPREP00000002849	ENSPREP00000008305	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.888
LOC103473053	dicer1	ENSPREP00000013374	ENSPREP00000017960	Uncharacterized protein; Belongs to the argonaute family.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.896
LOC103473053	drosha	ENSPREP00000013374	ENSPREP00000032952	Uncharacterized protein; Belongs to the argonaute family.	Drosha ribonuclease III.	0.655
LOC103473053	prkra	ENSPREP00000013374	ENSPREP00000008305	Uncharacterized protein; Belongs to the argonaute family.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.832
LOC103477270	prkra	ENSPREP00000011565	ENSPREP00000008305	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.871
LOC103477355	prkra	ENSPREP00000011646	ENSPREP00000008305	Protein kinase domain-containing protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.871
LOC103477771	ago4	ENSPREP00000009729	ENSPREP00000015301	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.552
LOC103477771	dicer1	ENSPREP00000009729	ENSPREP00000017960	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.896
LOC103477771	drosha	ENSPREP00000009729	ENSPREP00000032952	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Drosha ribonuclease III.	0.655
LOC103477771	prkra	ENSPREP00000009729	ENSPREP00000008305	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.888
LOC103477773	ago4	ENSPREP00000009674	ENSPREP00000015301	Argonaute RISC component 1; Belongs to the argonaute family.	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.551
LOC103477773	dicer1	ENSPREP00000009674	ENSPREP00000017960	Argonaute RISC component 1; Belongs to the argonaute family.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.896
LOC103477773	drosha	ENSPREP00000009674	ENSPREP00000032952	Argonaute RISC component 1; Belongs to the argonaute family.	Drosha ribonuclease III.	0.655
LOC103477773	prkra	ENSPREP00000009674	ENSPREP00000008305	Argonaute RISC component 1; Belongs to the argonaute family.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.888
ago4	LOC103472230	ENSPREP00000015301	ENSPREP00000002849	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.552
ago4	LOC103477771	ENSPREP00000015301	ENSPREP00000009729	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.	0.552