node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103473119 | acadm | ENSPREP00000017837 | ENSPREP00000027231 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acyl-CoA dehydrogenase medium chain. | 0.402 |
LOC103473119 | acat2 | ENSPREP00000017837 | ENSPREP00000008323 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.996 |
LOC103473119 | cs | ENSPREP00000017837 | ENSPREP00000033337 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Citrate synthase; Belongs to the citrate synthase family. | 0.860 |
LOC103473119 | eci2 | ENSPREP00000017837 | ENSPREP00000014783 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA delta isomerase 2. | 0.616 |
LOC103473119 | ehhadh | ENSPREP00000017837 | ENSPREP00000013997 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.957 |
LOC103473119 | hadh | ENSPREP00000017837 | ENSPREP00000003565 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase. | 0.922 |
LOC103473119 | hadha | ENSPREP00000017837 | ENSPREP00000021058 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.590 |
LOC103473119 | oxct1 | ENSPREP00000017837 | ENSPREP00000024269 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.956 |
acadm | LOC103473119 | ENSPREP00000027231 | ENSPREP00000017837 | Acyl-CoA dehydrogenase medium chain. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.402 |
acadm | acat2 | ENSPREP00000027231 | ENSPREP00000008323 | Acyl-CoA dehydrogenase medium chain. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.959 |
acadm | acox1 | ENSPREP00000027231 | ENSPREP00000029304 | Acyl-CoA dehydrogenase medium chain. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.959 |
acadm | acox3 | ENSPREP00000027231 | ENSPREP00000004131 | Acyl-CoA dehydrogenase medium chain. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.951 |
acadm | cs | ENSPREP00000027231 | ENSPREP00000033337 | Acyl-CoA dehydrogenase medium chain. | Citrate synthase; Belongs to the citrate synthase family. | 0.411 |
acadm | eci2 | ENSPREP00000027231 | ENSPREP00000014783 | Acyl-CoA dehydrogenase medium chain. | Enoyl-CoA delta isomerase 2. | 0.911 |
acadm | ehhadh | ENSPREP00000027231 | ENSPREP00000013997 | Acyl-CoA dehydrogenase medium chain. | Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.972 |
acadm | hadh | ENSPREP00000027231 | ENSPREP00000003565 | Acyl-CoA dehydrogenase medium chain. | Hydroxyacyl-CoA dehydrogenase. | 0.872 |
acadm | hadha | ENSPREP00000027231 | ENSPREP00000021058 | Acyl-CoA dehydrogenase medium chain. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.978 |
acadm | oxct1 | ENSPREP00000027231 | ENSPREP00000024269 | Acyl-CoA dehydrogenase medium chain. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.586 |
acat2 | LOC103473119 | ENSPREP00000008323 | ENSPREP00000017837 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.996 |
acat2 | acadm | ENSPREP00000008323 | ENSPREP00000027231 | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | Acyl-CoA dehydrogenase medium chain. | 0.959 |